Vaccine-preventable diseases

Clinical information

Vaccines help prevent infections, transmission and thus the spread of diseases or pathogens such as tetanus, diphtheria, Bordetella pertussis, tick-borne encephalitis virus (TBE), measles virus, rubella virus or varicella zoster virus (VZV).

Diagnostics

Detection of IgG antibodies in order to assess the immune status is only possible for some pathogens. This requires, e.g. standardised antibody detection based on international reference preparations and the availability of a cut-off to distinguish between existing or non-existent immunity. These values have been described for tetanus, diphtheria, measles, rubella, VZV and TBE. For mumps and pertussis, however, there are no values or markers for immunity known to correspond with immune protection.

Techniques

Method
Parameter
Substrate
Species
ELISA
diphtheria toxoid
antigen-coated
microplate wells
EUROLINE
positive control serum: IgA, human, 50x concentrated
for Bordetella pertussis
EUROLINE
positive control serum: IgG, human, 50x concentrated
for Bordetella pertussis
EUROLINE
Bordetella pertussis
(FHA, PT, ACT separately)
EUROLINE
ELISA
Bordetella pertussis
toxin
antigen-coated
microplate wells
ELISA
Bordetella pertussis
toxin
antigen-coated
microplate wells
ELISA
Bordetella pertussis
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
Bordetella
FHA
antigen-coated
microplate wells
ELISA
Bordetella
FHA
antigen-coated
microplate wells
ChLIA
IDS Tetanus IgG Control Set 1
3 x 1.5mL Control 1/2
ChLIA
IDS Tetanus IgG 1
antigenic coated magnetic particles
ELISA
tetanus toxoid
antigen-coated
microplate wells
ChLIA
IDS TOXO Avidity Control Set 1
3 x 1.0mL Control 1/2
EUROArray
EUROArray HPV
EUROArray
GynTect®
ChLIA
IDS Rubella Control Set 1
3 x 1.5mL Control 1/2
WESTERNBLOT
Rubella virus
Westernblot
ELISA
Rubella virus
antigen-coated
microplate wells
ChLIA
IDS Rubella IgG
1
antigenic coated magnetic particles
ChLIA
IDS Rubella IgM 1
antigenic coated magnetic particles
ChLIA
IDS Rubella Avidity Control Set 1
3 x 1.0mL Control 1/2
ELISA
Rubella virus
avidity determination
antigen-coated
microplate wells
ChLIA
IDS Rubella IgG Avidity 1
antigenic coated magnetic particles
ELISA
Rubella virus glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Rubella virus (IgG)
ELISA
Rubella virus
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Measles virus
antigen-coated
microplate wells
ELISA
Measles virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
ChLIA
IDS Measles IgG 1
antigenic coated magnetic particles
ChLIA
IDS Measles IgM 1
antigenic coated magnetic particles
ELISA
Measles virus
avidity determination
antigen-coated
microplate wells
ELISA
Measles virus NP: recombinant nucleoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Measles virus (IgG)
ELISA
Measles virus
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Mumps virus
antigen-coated
microplate wells
ELISA
Mumps virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
ChLIA
IDS Mumps IgG 1
antigenic coated magnetic particles
ChLIA
IDS Mumps IgM 1
antigenic coated magnetic particles
ELISA
Mumps virus AT: strains "Enders"
and "Jeryl Lynn"
antigen-coated
microplate wells
ELISA
Mumps virus G5: native antigens,
genotype "G5"
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Mumps virus (IgG)
ELISA
Mumps virus
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Varicella zoster virus
(VZV)
antigen-coated
microplate wells
ELISA
Varicella zoster virus
(VZV)
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
ChLIA
IDS VZV IgG 1
antigenic coated magnetic particles
ChLIA
IDS VZV IgM 1
antigenic coated magnetic particles
IIFT
Varicella zoster virus
(VZV)
infected cells
EU 168
ELISA
Varicella zoster virus (VZV)
avidity determination
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV) glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-VZV (IgG)
ELISA
Varicella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
ChLIA
IDS MMV IgG Control Set 1
3 x 1.5mL Control 1/2
ChLIA
IDS MMV IgM Control Set 1
3 x 1.5mL Control 1/2
ELISA
TBE virus
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
TBE virus (TBEV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Flavivirus Mosaic 1
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
4 BIOCHIPs per field:
infected cells
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
EU 14
ELISA
Anti-TBE Virus ELISA 2.0 (IgG)
antigen-coated
microplate wells
IIFT
Flavivirus Profile 2
upper row:
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)
bottom row:
Dengue virus
types 1 - 4 (DENV)


infected cells
infected cells
infected cells
infected cells

infected cells


EU 14
EU 14
EU 14
EU 14

EU 14
ELISA
Anti-TBE Virus CSF ELISA 2.0 (IgG)
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-TBE virus (IgM)
ELISA
TBE virus
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Influenza virus type A
antigen-coated
microplate wells
ELISA
Influenza virus type A
antigen-coated
microplate wells
ELISA
Influenza virus type B
antigen-coated
microplate wells
ELISA
Influenza virus type B
antigen-coated
microplate wells
1Product manufactured by third party. Please contact your local EUROIMMUN representative for more information.
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