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Lyme ELISA (IgG/IgM): combination of recombinant VlsE and OspC for simultaneous detection of IgG and IgM antibodies
Lyme disease is a tick-borne disease caused by bacteria of the genus Borrelia. The diagnosis of Lyme disease is based on the patient anamnesis, clinical findings and the detection of antibodies against Borrelia antigens.
The EUROIMMUN Lyme ELISA (IgG/IgM) allows reliable diagnosis of borreliosis already in early disease stages, provided that detectable antibodies are present. The ELISA uses VlsE and OspC, which are the major target antigens in the IgG and IgM mediated immune response to a Borrelia infection. IgM antibodies against OspC and IgG antibodies against VlsE are produced very early after infection.