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Calprotectin ELISA: sensitive marker for chronic inflammatory bowel diseases (CIBD)

Calprotectin ELISA correlates very well with the histological and endoscopic findings in patients with CIBD. This assay spares the patient complicated and time-consuming imaging pictures, biopsies and the cost-intensive and radiation-intensive stool test. Increased calprotectin values indicate with great certainty and acute or chronic IBD or a recurrent IBD. Calprotectin is an ideal marker to monitor the disease course e.g. in Crohn’s disease or after removal of colorectal polyps.

The measurement of the calprotectin level is particularly suited for the diagnostic differentiation between irritable bowel syndrome (IBS) and chronic inflammatory bowel diseases (CIBD) due to its high predictive value.